Envepe Tablets Specification
Requires Prescription (YES/NO)
Yes
Generics
Doxylamine succinate + Pyridoxine HCl
Used For
Nausea Vomiting of Pregnancy
How it works
It contains two medicines (‘active substances’) called: ‘Doxylamine succinate’ and ‘Pyridoxine hydrochloride’. • Doxylamine succinate belongs to a group of medicines called ‘antihistamines’. • Pyridoxine hydrochloride is another name for Vitamin B6. Doxylamine succinate is a member of the first-generation class of antihistamines, doxylamine exerts its effects by competitively antagonizing the binding of free histamine at the H1-receptor binding sites. It antagonizes the effects of histamine in the uterus, GI tract, large blood vessels, and bronchial muscles.
Envepe Tablets Usage And Safety
Dosage
Doxylamine succinate + Pyridoxine HCl
Side Effects
Very common: may affect more than 1 in 10 people • Feeling very sleepy. Common: may affect up to 1 in 10 people • Feeling dizzy • feeling tired • dry mouth. Not known: Frequency cannot be estimated from the available data • hypersensitivity (allergic reaction) • feeling anxious, difficulty in sleeping (insomnia), nightmares, feeling disorientated • headaches or migraines • tingling, pricking or numbness of skin • restlessness and a need to move constantly • problems with eyesight or blurred vision • sensation of spinning dizziness • difficulty breathing, awareness of heartbeat or increased heart rate • full or bloated feeling, stomach pains, constipation or diarrhoea • excessive sweating, skin reactions such as itchiness or rash • difficulties or pain with passing urine
Drug Interactions
MAOIs , CND depressants such as hypnotics , sedatives, tranquilisers.
Indication
It is used in pregnant women, to help stop them feeling sick (nausea) and being sick (vomiting).
When not to Use
Do not take if: • You are allergic to doxylamine succinate or other antihistamines (such as diphenhydramine), pyridoxine hydrochloride or any of the other ingredients of this medicine • You are taking medicines for depression called ‘monoamine oxidase inhibitors’ (MAOIs).
Envepe Tablets Precautions
Precaution
If you suffer from severe nausea and vomiting of pregnancy, a condition called hyperemesis gravidarum, you have to be treated by a specialist.
Envepe Tablets Warnings
Warning 1
Talk to your doctor, pharmacist or nurse before taking any additional vitamin B – this could be through your diet, from supplements or multi-vitamins.
Warning 2
Talk to your doctor or pharmacist or nurse before taking if you have ever had an eye problem called ‘narrow angle glaucoma’ .
Warning 3
Talk to your doctor or pharmacist or nurse before taking if you have ever had a blockage in your gut, between your stomach and small intestine .
Envepe Tablets Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
