COFREST SYRUP 120ML
Brand: Woodward Pakistan (Pvt) Ltd
Regular price
Rs: 104.00
Rs: 98.00
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Rs: 6.00
(6%)
Cofrest Syrup Specification
Requires Prescription (YES/NO)
Yes
Generics
Theophylline, Diphenhydramine, Ammonium Chloride, Menthol
Used For
Fever & Cough
How it works
Theophylline relaxes the smooth muscles in the bronchial airways and pulmonary blood vessels. Ammonium chloride increases acidity by increasing the amount of hydrogen ion concentrations. Ammonium chloride can be used as an expectorant due to its irritative action on the bronchial mucosa. It acts as a counter-irritant by imparting a cooling effect and by initially stimulating nociceptors and then desensitizing them. Diphenhydramine acts as an inverse agonist at the H1 receptor, thereby reversing the effects of histamine on capillaries, and reducing allergic reaction symptoms.
Cofrest Syrup Usage And Safety
Dosage
Theophylline, Diphenhydramine, Ammonium Chloride, Menthol
Side Effects
Hypersensitivity, Hypokalemia, hyperglycaemia, electrolyte imbalance, Agitation, restlessness, irritability, nervousness, Headache, insomnia, tremor, convulsions, Heart rate increased, heart rate irregular, palpitations, arrhythmia, ventricular, arrhythmia, tachycardia, sinus tachycardia, supraventricular tachycardia, atrial tachycardia and atria flutter, Hypotension, shock, Nausea, vomiting, diarrhoea, gastrointestinal disorder including gastrointestinal haemorrhage, abdominal pain, haematemesis.
Drug Interactions
Alcohol , Allopurinol , Aminoglutethimide , Barbiturates , Diazepam , Cimetidine , Disulfiram , Erythromycin , Estrogen , Fluvoxamine , Formoterol , Halothane , Imipenem , Isoniazid , Lithium , Macrolides (josamycin,spiramycin) Methotrexate (MTX) , Mexiletine , Moricizine , Pentoxifylline , Phenobarbital , Phenytoin ,Primidone , Propafenone , Propranolol , Rifampin , Sulfinpyrazone , Tacrine , Thiabendazole , Ticlopidine, Troleandomycin , Verapamil , Zileuton.
Indication
Reversible airflow obstruction, Relief of runny nose, Sneezing, Itchy, Watery eyes, Itchy nose, Itchy throat due to hay fever or allergy.
When Not to Use
Hypersensitivity to the ingredients listed.
Cofrest Syrup Precautions
Precaution
Theophylline should be used with caution and only if necessary in the following cases: Unstable angina, Patients at risk of tachyarrhythmia, Severe hypertension, Hypertrophic obstructive cardiomyopathy, and Hyperthyroidism.
Cofrest Syrup Warnings
Warning 1
Patients administering Ammonium chloride should be watched for signs of ammonia toxicity.
Warning 2
Diphenhydramine may make you dizzy and can blur vision.
Warning 3
Theophylline should be used with caution in patients with hepatic or renal function impairment.
Cofrest Syrup Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
