Actrapid Hm Specification
Requires Prescription (YES/NO)
Yes
Generics
Human Insulin
Used For
Diabetes Management
How it works
The major effects of insulin on carbohydrate homoeostasis following its binding to specific cell-surface receptors on insulin-sensitive tissues, notably the liver, muscles and adipose tissue. It inhibits hepatic glucose production and enhances peripheral glucose disposal thereby reducing blood-glucose concentration. It also inhibits lipolysis thereby preventing the formation of ketone bodies.
Actrapid Hm Usage And Safety
Dosage
Human Insulin
Side Effects
Hypoglycemia : They may include cold sweat, cool pale skin, nervousness or tremor, anxious feeling, unusual tiredness or weakness, confusion, difficulty in concentration, headache, nausea and palpitation. Severe hypoglycemia may lead to unconsciousness and may result in temporary or permanent impairment of brain function or even death , Weight gain , Oedema and refraction anomalies , . Local hypersensitivity reactions (redness, swelling and itching at the injection site) , Lipodystrophy , generalised skin rash, itching, sweating, gastrointestinal upset, angioneurotic oedema, difficulties in breathing, palpitation and reduction in blood pressure.
Drug Interactions
Beta blocking agent Oral hypoglycemic agents (OHA), octreotide, monoamine oxidase inhibitor (MAOI), non selective beta blocking agents, angiotensin converting enzyme (ACE) inhibitors, salicylates, alcohol and alcohol steroids , Oral contraceptives, thiazides, glucocorticoids, thyroid hormones and sympathomimetics, danazol etc.
Indication
It is indicated for the treatment of : Patients with Type I diabetes mellitus. - Patients with Type II diabetes mellitus either alone or in combination with oral anti-diabetic agents. - Patients with gestational diabetes. - The emergency management of diabetic ketoacidosis.
When not to Use
Insulin is contraindicated in: - Patients with hypersensitivity to any components of this medication. - Patients with hypoglycemia. - Patients in coma due to hyperglycemia.
Actrapid Hm Precautions
Precaution
Care is also necessary during excessive exercise. Hypoglycemia caused by metabolic effects and increased insulin absorption is the usual response, but hyperglycemia may sometimes occur. Adjustment of insulin dosage may also be necessary if patients change their level of physical activity or change their usual diet.
Actrapid Hm Warnings
Warning 1
Insulin requirements may be increased during illness or emotional disturbances.
Warning 2
The use of insulin necessitates monitoring of therapy, such as the testing of blood or urine for glucose concentrations and the urine for ketones, by the patient .
Warning 3
Local reactions, characterised hypersensitivity may produce urticaria, angioedema and very rarely anaphylactic reactions. If continued therapy with insulin is essential, hyposensitisation procedures may need to be performed.
Actrapid Hm Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store in a refrigerator (2°C–8°C). Do not Freeze .
